Preheat a griddle to 325°F, or a skillet over medium-high heat. Melt 1/4 cup butter in the microwave and set aside to cool for 3 minutes.
In a large bowl, whisk together 2 cups flour, 1/4 cup sugar, 2 teaspoons baking powder, 1 1/2 teaspoons baking soda, and 3/4 teaspoon salt. Stir in the 2 cups buttermilk and melted butter just until combined. Mix in the 2 eggs and 2 teaspoons vanilla, just until most the lumps are gone and the batter is smooth. If the batter is too thick, add another splash of milk. If it's too thin add 1 Tablespoon flour.
Coat the griddle (or skillet) with butter. Pour 1/4 cup batter into individual circles. Cook 2 minutes, or until bubbles appear. Flip and cook 1 minute, or just until lightly browned.
Serve immediately or place on a baking sheet in the oven at 175°F to keep warm.
Notes
Storage: Once the buttermilk pancakes have completely cooled, store them in an airtight container in the refrigerator up to 4 days.Freeze: Let cool and then place in a large zip-top bag. Place in freezer for use within 2 to 3 months. When ready to eat, reheat in the microwave or toaster oven for 30 seconds.Reheat: Pop them in the microwave for a softer texture or the toaster for a slightly crispier bite.